Sesame Weight Loss Reviews – 14 GLP-1 Options with Insurance Support

Sesame (sesamecare.com) is a New York-based telehealth platform offering one of the widest medication selections in the GLP-1 space—14 prescription options including brand-name Wegovy, Zepbound, Ozempic, Mounjaro, and compounded semaglutide. Their Success by Sesame program starts at $99/month for telehealth and messaging, but medication costs are additional ($249+ for compounded, $499+ for brand-name). With a 4.5 Trustpilot rating across 4,000+ reviews and an A BBB rating, the trust signals are strong. However, 104 BBB complaints about billing issues and cancellation difficulty, plus a confusing 28-day billing cycle, require careful consideration. Here's our complete analysis.

What Is Sesame?

Sesame is a telehealth marketplace based in New York that connects patients with healthcare providers for a range of services, including their dedicated weight loss program called Success by Sesame. Unlike many GLP-1 telehealth startups, Sesame has been around since before the weight loss boom and expanded into the GLP-1 space with a comprehensive approach that includes both insured and uninsured patients.

What genuinely sets Sesame apart is medication variety. With 14 prescription options—including brand-name Wegovy, Zepbound, Ozempic, Mounjaro, Rybelsus, and compounded semaglutide—patients have more choices than almost any other telehealth GLP-1 provider. The platform also lets patients choose their own provider, which is uncommon in this space and gives patients more control over their care.

Sesame accepts both insured and uninsured patients and offers insurance pre-authorization support for brand-name medications. For patients with insurance coverage, brand-name GLP-1s can drop to as low as $25/month—a fraction of the typical out-of-pocket cost. This insurance navigation is a real differentiator for patients who have coverage but struggle with the pre-authorization process.

What They Offer

• 14 prescription options including Wegovy, Zepbound, Ozempic, Mounjaro, Rybelsus, and compounded semaglutide
• Success by Sesame program starting at $99/month (telehealth + messaging)
• Same-day consultations available
• Unlimited video visits and chat with your provider
• Insurance pre-authorization support for brand-name medications
• Both insured and uninsured patients accepted
• Patient chooses their own provider
• Costco member pricing — $179 for initial 3-month subscription
• BBB accredited since 2022 with A rating
• Brand-name medications available — not just compounded

The ability to choose your own provider and access same-day consultations are meaningful advantages. Many GLP-1 telehealth services assign you a random provider with limited availability. Sesame's marketplace model gives patients agency, though it also means provider quality can vary depending on who you select.

Sesame Pricing

Sesame's pricing structure is more complex than most GLP-1 providers because it separates the program fee from medication costs. The $99/month Success by Sesame fee covers telehealth visits and messaging, but medication is billed separately.

The total cost for self-pay patients using compounded semaglutide is approximately $348/month ($99 program + $249 medication)—significantly more than CoreAge Rx's all-inclusive $99/month. Even the program fee alone matches CoreAge Rx's total price. For insured patients seeking brand-name medications, however, the math changes dramatically: $99/month program fee plus a $25 copay totals $124/month for brand-name Wegovy or Zepbound, which is excellent value.

The Costco member deal at $179 for the initial 3-month subscription provides a meaningful discount for those first months. If you're already a Costco member, this lowers the barrier to trying the service.

My Experience With Sesame

I tested Sesame's Success by Sesame program to evaluate their provider marketplace model and whether the wide medication selection lives up to its promise. Here's what I found:

Sign-Up Process

Signing up for Sesame was straightforward. The platform presents available providers in your area with their credentials, ratings, and availability. Being able to browse and select your own provider felt empowering compared to being randomly assigned one. I chose a provider with strong reviews and booked a same-day video consultation—a genuine advantage over providers with multi-day wait times.

The onboarding process required standard health information and insurance details (if applicable). The interface was clean, though the pricing structure took some effort to fully understand—the separation of program fees from medication costs wasn't immediately obvious during sign-up.

Consultation Quality

The video consultation was thorough. My provider discussed my weight loss goals, medical history, and walked through the available medication options—explaining the differences between compounded and brand-name GLP-1s. The ability to have unlimited follow-up video visits and chat messaging meant I could ask questions after the initial consultation without additional charges.

However, provider quality on Sesame is variable because it's a marketplace. Some Trustpilot reviewers report excellent provider experiences while others describe providers who seemed rushed or dismissive. Since you choose your own provider, reading reviews before booking is essential. The platform doesn't offer intensive nutrition coaching or structured lifestyle support—it's primarily a prescription service with provider access.

Insurance Navigation

One area where Sesame genuinely excels is insurance pre-authorization support. For patients with insurance that may cover brand-name GLP-1 medications, Sesame's team helps navigate the often-frustrating pre-authorization process. This can be the difference between paying $499+/month out of pocket and $25/month with insurance. For insured patients, this service alone could justify the $99/month program fee.

Customer Support and Billing

Customer support was generally responsive, but the 104 BBB complaints paint a different picture for some patients. The most common issues involve billing disputes, difficulty cancelling subscriptions, and prescription errors. Multiple reviewers report being charged after requesting cancellation—a serious concern for any subscription service. The 28-day billing cycle also catches some patients off guard, as many assume they're paying monthly.

The mobile app receives mixed reviews, with some users reporting bugs and glitches that complicate appointment scheduling and messaging. Geographic restrictions for lab work in 9 states add another layer of inconvenience for patients in those areas.

Pros and Cons

Is Sesame Legit?

Yes, Sesame is a legitimate and established telehealth provider with strong trust signals. The A BBB rating with accreditation since 2022 and a 4.5 Trustpilot rating across 4,000+ reviews are among the better credibility indicators in the GLP-1 telehealth space. Sesame also responds to 89% of negative Trustpilot reviews, showing active engagement with customer concerns.

The company is based in New York and operates as a healthcare marketplace connecting patients with licensed providers. This is a well-established business model (similar to Zocdoc) applied to the GLP-1 weight loss space. The fact that they offer brand-name FDA-approved medications alongside compounded options demonstrates a more comprehensive approach than providers limited to compounded-only medications.

The 104 BBB complaints are the primary concern. While this number is manageable for a company of Sesame's size, the patterns are worth noting: billing issues after cancellation, difficulty reaching support to cancel, prescription errors, and geographic limitations for lab work. These are operational issues, not legitimacy concerns—but they indicate areas where the customer experience can fall short.

• A BBB rating — accredited since 2022
• 4.5 Trustpilot rating with 4,000+ reviews
• 89% negative review response rate on Trustpilot
• New York-based company with established marketplace model
• Brand-name FDA-approved medications available
• 104 BBB complaints — billing and cancellation issues are the main concerns

Who Is Sesame Best For?

Sesame is ideal for insured patients who want brand-name GLP-1 medications with pre-authorization support. If your insurance covers Wegovy, Zepbound, or other brand-name GLP-1s, Sesame's $99/month program fee plus a potential $25 copay is excellent value for brand-name medication access. The insurance navigation support is a genuine differentiator that can save hundreds per month.

Sesame is also a strong choice for patients who want maximum medication flexibility. With 14 prescription options, you're not locked into a single medication type. If compounded semaglutide isn't working, your provider can explore brand-name alternatives, tirzepatide options, or oral medications like Rybelsus—all within the same platform.

Sesame may not be the best fit if: You're self-pay and want the lowest total cost (CoreAge Rx is $99/month all-inclusive vs. Sesame's $348+ for compounded semaglutide), you prefer simple pricing without separated fees, or you've had negative experiences with subscription services that are difficult to cancel.

Final Verdict: Is Sesame Worth It?

Sesame is one of the stronger GLP-1 providers available, with excellent trust signals and the widest medication selection we've reviewed.

The combination of a 4.5 Trustpilot rating, A BBB rating, 14 prescription options, provider choice, same-day consultations, and insurance support creates a comprehensive package that few competitors can match. For insured patients, the total cost of $124/month for brand-name GLP-1 medications is genuinely competitive. The 89% negative review response rate shows a company that takes customer feedback seriously.

However, the economics are unfavorable for self-pay patients. At $348/month for compounded semaglutide ($99 program + $249 medication), Sesame costs 3.5x more than CoreAge Rx's all-inclusive $99/month. The 28-day billing cycle adds another 8% to annual costs—a detail that feels deliberately opaque. And with 104 BBB complaints focused on billing and cancellation issues, some patients clearly struggle with the subscription experience.

My recommendation: Sesame is a top choice for insured patients who want brand-name medication access with pre-authorization support. For self-pay patients seeking compounded semaglutide, CoreAge Rx at $99/month is the better value. Sesame's medication variety and provider choice are real strengths, but the total cost for uninsured patients significantly exceeds alternatives.

The Bottom Line

Sesame is a well-established telehealth platform with the widest GLP-1 medication selection available, strong Trustpilot and BBB ratings, and valuable insurance navigation support. For insured patients, it's one of the best options for accessing brand-name medications at reasonable costs. For self-pay patients, the total cost of $348+/month for compounded semaglutide makes CoreAge Rx at $99/month the clear value leader. Sesame earns a 3.8/5 rating—strong on trust and variety, but the cost structure and billing complaints hold it back from the top tier for uninsured patients.