SkinnyRx Weight Loss Reviews - Multiple GLP-1 Formats, But at What Cost?

SkinnyRx (skinnyrx.com) is a Sacramento, California-based telehealth provider offering one of the widest selections of GLP-1 medication formats we've seen — injectable semaglutide, sublingual (daily liquid) semaglutide, semaglutide tablets, and tirzepatide in both injectable and tablet forms. Their 4.8 Trustpilot rating across 4,482 reviews is genuinely impressive, and the money-back guarantee if you don't lose 10% body weight reduces financial risk. However, 107 BBB complaints, reports of weight gain despite medication, 12-day medical response waits, and pricing starting at $199/month — double CoreAge Rx's $99 — paint a more complicated picture. Here's our complete analysis.

What Is SkinnyRx?

SkinnyRx is a telehealth weight loss platform based in Sacramento, California that specializes in compounded GLP-1 medications. What distinguishes SkinnyRx from most competitors is the breadth of medication formats available — you're not limited to just injectable semaglutide. They offer sublingual semaglutide (a daily liquid taken under the tongue), semaglutide tablets, and tirzepatide in both injectable and tablet forms.

The format variety is a genuine differentiator. Many patients struggle with self-injections or prefer the convenience of an oral medication, and SkinnyRx addresses this barrier directly. The sublingual option is particularly uncommon — few providers offer a daily liquid alternative to weekly injections.

SkinnyRx also offers a money-back guarantee: if you don't lose 10% of your body weight, they'll refund your money. This is a bold promise that few GLP-1 providers make and signals confidence in their product. Free overnight shipping and FSA/HSA acceptance round out the offering.

What They Offer

• Injectable semaglutide starting at $199/month
• Sublingual semaglutide (daily liquid) starting at $199/month
• Semaglutide tablets at $249/month
• Tirzepatide (injectable and tablets) at $299/month
• Online medical evaluation — no in-person visits required
• Free overnight shipping on all orders
• FSA/HSA accepted — no insurance required
• Money-back guarantee if no 10% body weight loss
• Multiple medication formats — injectable, sublingual, and tablet options

SkinnyRx Pricing

SkinnyRx's pricing is significantly higher than the most affordable GLP-1 providers, though they argue the multiple format options and money-back guarantee justify the premium.

The semaglutide tablet option at $249/month is a premium convenience play — tablets are easier for patients who dislike injections or sublingual dosing, but you're paying a $50/month premium over the injectable and sublingual formats. Tirzepatide at $299/month is roughly in line with the broader market, though still meaningfully above the most competitive providers.

The free overnight shipping is a nice perk that most providers don't offer — many charge for expedited delivery or only include standard shipping. Combined with the money-back guarantee, SkinnyRx is clearly trying to reduce purchase anxiety and justify the higher price point.

My Experience With SkinnyRx

I evaluated SkinnyRx to test whether the format variety and money-back guarantee deliver genuine value at the higher price point. Here's what I found:

Sign-Up Process

The sign-up process involves an online medical evaluation — standard health questionnaire reviewed by their medical team. The format selection is where SkinnyRx shines: you can choose between injectable, sublingual, or tablet forms of semaglutide, plus tirzepatide options. Having these choices upfront is genuinely helpful for patients with injection anxiety or lifestyle preferences.

Medical Oversight Concerns

This is where the experience deteriorates significantly. Multiple BBB complaints describe SkinnyRx's approach as highly transactional — get the prescription, ship the medication, minimal follow-up. Several patients reported a complete lack of meaningful medical guidance or coaching throughout their treatment.

The most alarming complaint involves 12-day waits for medical team responses. When you're taking prescription medication that can cause serious side effects, waiting nearly two weeks for a response from your medical team is unacceptable. GLP-1 medications require proper dosing titration and monitoring — patients experiencing nausea, vomiting, or other side effects need timely medical guidance, not a 12-day queue.

Effectiveness Reports

While 92% of Trustpilot reviews are five-star, BBB complaints tell a different story for some patients. Multiple reviewers reported weight gain despite taking medication and following diet and exercise recommendations. This is particularly concerning because it suggests that for some patients, the medication simply isn't working — and the medical team isn't adjusting the approach.

It's worth noting that GLP-1 medications don't work for everyone, and individual results vary. But a provider with proper medical oversight should be identifying non-responders early and adjusting treatment plans accordingly — not leaving patients on ineffective regimens for extended periods.

Cancellation Issues

Subscription cancellation difficulties are a recurring theme in BBB complaints. Multiple patients report trouble canceling their subscriptions and being charged after attempting to discontinue service. Misleading marketing claims were also cited — some patients felt the service was presented differently than what they received. These friction points are a red flag for any subscription-based healthcare service.

Pros and Cons

Is SkinnyRx Legit?

SkinnyRx is a legitimate telehealth provider, but legitimacy and quality are different things. They are a real business based in Sacramento, California, with a BBB listing (B rating, not accredited) and a strong Trustpilot presence. The medications they provide are real compounded GLP-1 formulations.

The 4.8 Trustpilot rating across 4,482 reviews is one of the strongest we've seen in the GLP-1 telehealth space — and 92% five-star reviews is genuinely impressive. This isn't a scam operation; thousands of customers have had positive experiences with real weight loss results.

However, 107 BBB complaints is a significant number that can't be dismissed. For context, many GLP-1 providers we review have fewer than 20 BBB complaints. The nature of the complaints — ineffectiveness, cancellation difficulties, misleading marketing, and slow medical responses — suggests systemic operational issues rather than isolated incidents.

• 4.8 Trustpilot rating with 4,482 reviews — among the strongest we've seen
• BBB B rating in Sacramento, California — not accredited
• 107 BBB complaints — significantly above average for GLP-1 providers
• Real compounded GLP-1 medications in multiple formats
• Money-back guarantee provides financial protection
• Medical oversight concerns — 12-day response waits and minimal coaching

Who Is SkinnyRx Best For?

SkinnyRx is best suited for patients who need non-injectable GLP-1 options and are willing to pay a premium for format flexibility. If you have injection anxiety or strongly prefer a daily sublingual liquid or tablet over weekly injections, SkinnyRx offers alternatives that most providers simply don't have.

The money-back guarantee also makes SkinnyRx appealing for patients who are uncertain whether GLP-1 medication will work for them. The promise of a refund if you don't lose 10% of your body weight reduces the financial risk of trying an expensive treatment.

SkinnyRx is not the best fit if: You want the most affordable GLP-1 option (CoreAge Rx is $99/month — half the price), you expect responsive medical oversight and coaching, you've had difficulty canceling subscriptions in the past, or you prefer a provider with minimal BBB complaints.

Final Verdict: Is SkinnyRx Worth It?

SkinnyRx is a mixed bag — strong Trustpilot reputation and genuine format variety, but overpriced with concerning medical oversight gaps.

The positives are real: a 4.8 Trustpilot rating with 4,482 reviews (92% five-star) is among the strongest social proof we've encountered. The multiple medication formats — injectable, sublingual, and tablets for both semaglutide and tirzepatide — are a genuine competitive advantage. The money-back guarantee and free overnight shipping add tangible value. For patients who specifically need non-injectable options, SkinnyRx fills a real gap in the market.

But the negatives are equally real: 107 BBB complaints is far above average. Reports of 12-day medical response waits are frankly dangerous for patients on prescription medication. Weight gain despite medication compliance suggests some patients aren't receiving adequate medical oversight or dosing adjustments. Subscription cancellation difficulties and misleading marketing allegations erode trust. And at $199/month, you're paying exactly double what CoreAge Rx charges for semaglutide with arguably better medical support.

My recommendation: If you specifically need sublingual or tablet GLP-1 options that you can't find elsewhere, SkinnyRx's format variety is worth considering — and the money-back guarantee reduces your risk. But for most patients seeking standard injectable semaglutide, CoreAge Rx at $99/month delivers better value with more responsive medical oversight. The $100/month savings adds up to $1,200/year — a significant difference for the same active ingredient.

The Bottom Line

SkinnyRx has an impressive Trustpilot reputation and offers the widest GLP-1 format selection we've reviewed — injectable, sublingual, and tablet options for both semaglutide and tirzepatide. The money-back guarantee is a confidence signal. But at $199/month (double CoreAge Rx), with 107 BBB complaints, 12-day medical response waits, and reports of minimal clinical guidance, the premium price doesn't match the premium experience patients deserve. Format variety is a genuine advantage; the rest needs significant improvement.