Affiliate disclosure
We earn a commission if you sign up with MangoRx through the links on this page. It did not buy a favourable review.
MangoRx is a men’s health platform — ED, hair loss, hormones, testosterone — that has added a GLP-1 weight-loss line called Slim, offering compounded semaglutide and tirzepatide. We cannot tell you what it costs, and neither can MangoRx’s website: the price is quoted only after you complete an eligibility questionnaire and a full medical intake. For a category where the spread runs from $69 to $599 a month, that is a serious problem before you get to the Eli Lilly lawsuit.
Overview
MangoRx is operated by Mangoceuticals, a publicly traded company (NASDAQ: MGRX) based in Dallas. Its original and best-known product is Mango, a rapid-dissolve ED tablet; the range has since grown to include Grow for hair loss, Mojo for hormones, Prime for oral testosterone, and Slim, the GLP-1 weight-loss line. Slim is newer than the core business and the independent review record reflects that.
MangoRx at a Glance
| Medications offered | Slim line: compounded semaglutide and compounded tirzepatide. Wider platform covers ED, hair loss, hormones and oral testosterone. |
|---|---|
| Brand-name or compounded | Compounded — not FDA-approved finished products |
| Consultation process | Eligibility questionnaire plus medical intake, reviewed by a provider |
| Eligibility | Assessed after intake; around a dozen US states are excluded |
| Provider involvement | Provider review and dose recommendation, after which a price is quoted |
| Lab requirements | Not stated as required |
| Pharmacy fulfillment | Not named |
| Shipping frequency | Not detailed for the Slim line; reported customer ratings around 4.5 for shipping on the wider business |
| Support services | Reported customer service rating around 4.5 on the wider business |
| Membership fees | Not published |
| Medication fees | Not published — quoted only after the intake and provider review |
| Cancellation policy | Not published |
| Refund policy | Not published |
| Insurance | Not stated |
| HSA/FSA | Not stated |
| Availability | US only, with around a dozen states excluded |
You Cannot See the Price Before You Apply
MangoRx does not publish Slim GLP-1 pricing. You complete the eligibility questionnaire and medical intake, and a final price is quoted once a provider has reviewed your information and recommended a dose.
Every provider in this category has some pricing opacity — starting-dose figures that rise on titration, plan-length discounts, membership fees quoted separately. MangoRx goes further than any of them by publishing no figure at all.
The practical consequences are worth spelling out. You cannot comparison shop, which is the single most valuable thing a patient can do in a market where the same compounded semaglutide runs $69 at Embody and $497 at Direct Meds for tirzepatide. You have to disclose your medical history — weight, health conditions, medications — to a commercial entity before learning whether the offer is even affordable. And by the time a number appears you have invested time and personal information, which is a well-understood way to make people more likely to accept whatever is quoted.
We are not suggesting the eventual price is unfair; we have no way to know, which is the point. There is also a legitimate clinical argument for it — the price genuinely does depend on the dose a provider recommends. But MadeMed publishes a price against every dose and HealthRX charges the same at every dose, so the problem is clearly solvable.
If you do apply, get the full schedule in writing including what happens as your dose escalates, and treat the quote as the start of a comparison rather than the end of one. Our cheapest programs page gives you the numbers to check it against.
The Eli Lilly Lawsuit
The company is in litigation with Eli Lilly, which alleges it improperly copied Lilly’s weight-loss medicines Zepbound and Mounjaro. These are allegations in an active dispute, not findings of fact.
Eli Lilly has brought a series of actions against telehealth platforms and compounders over compounded tirzepatide, so MangoRx is not uniquely targeted — this is a broad industry campaign. You should weigh it accordingly, and you should not read it as a finding that MangoRx did anything wrong.
What it does bear on is continuity of supply. Tirzepatide is Lilly’s patented molecule, and the legal position of compounded tirzepatide has narrowed considerably since the FDA declared the shortage resolved — compounders lost the shortage-based justification for producing copies of a commercially available drug. If you start a course of compounded tirzepatide with a provider facing active litigation from the patent holder, there is a real possibility that the product becomes unavailable partway through your treatment. That is disruptive in a medication you titrate over months.
The practical mitigation is to ask what happens to your supply if the product is withdrawn, and to prefer providers offering an FDA-approved route as a fallback. CVS Health at $149 self-pay and LillyDirect from $299 both sell the genuine article with no such exposure. Our claims and risks guide covers the wider enforcement picture.
A Dozen States Are Excluded
Around a dozen US states are reported to be off-limits for the Slim line. That is a wider exclusion than most competitors — JRNYS and Luvo Health both operate in all 50 — and combined with gated pricing it means you may complete an intake only to discover you cannot be served at all. Check availability in your state before you start the questionnaire.
Eligibility, Contraindications, and Side Effects
Eligibility is determined after the questionnaire and medical intake; published criteria are thin. See our eligibility guide.
Semaglutide and tirzepatide carry a boxed warning regarding thyroid C-cell tumours, based on rodent studies. Do not take these medications if you or a family member have had medullary thyroid carcinoma, if you have Multiple Endocrine Neoplasia syndrome type 2, or if you have had a serious hypersensitivity reaction to the active ingredient. They are not for use in pregnancy. Disclose any history of pancreatitis, gallbladder disease, gastroparesis or other severe gastrointestinal disease, or diabetic retinopathy.
Common side effects are gastrointestinal — nausea, vomiting, diarrhoea, constipation, abdominal pain — worst after dose increases. Serious but less common: pancreatitis, gallbladder disease, acute kidney injury from dehydration. See our side effects guide.
One point specific to a platform selling testosterone and hormone products alongside GLP-1s: if you are taking anything else from the MangoRx range, make sure the prescriber knows. Combining testosterone therapy with rapid GLP-1 weight loss changes several things at once — body composition, haematocrit, blood pressure — and warrants monitoring nobody has described here.
Confirm your compounded dose in both units and milligrams, and confirm the vial concentration. The FDA has documented five to ten-fold overdoses caused by unit-to-milligram conversion errors.
How MangoRx Compares
| Provider | Price published? | States | Litigation | Our rating |
|---|---|---|---|---|
| MangoRx | No — gated behind intake | ~12 excluded | Eli Lilly suit | 2.8 / 5 |
| HealthRX | Yes — same at every dose | Not published | None found | 3.8 / 5 |
| MadeMed | Yes — per dose | Not published | None found | 3.4 / 5 |
| CVS Health | Yes — $149 self-pay | Nationwide | n/a — FDA-approved | 4.4 / 5 |
Pros and Cons
Pros
- Both compounded semaglutide and tirzepatide offered
- Reported shipping and customer service ratings around 4.5 on the wider business
- A publicly traded company, so financial disclosures are on the public record
- Convenient if you already use MangoRx for other men’s health products
- Dose recommended by a provider before pricing is set
Cons
- No published pricing at all — you must apply to find out
- Requires disclosing medical history before learning the cost
- Around a dozen states excluded
- Eli Lilly litigation over the weight-loss products
- Compounded tirzepatide supply carries real continuity risk
- Independent reviews of the Slim line specifically are thin
- Compounding pharmacy, cancellation and refund terms not published
Who Should Pick It, and Who Should Look Elsewhere
MangoRx suits you if you are already a MangoRx customer for ED or testosterone, value having one platform for everything, and are willing to complete an intake to discover the price. Check your state first, get the full escalated-dose schedule in writing, and compare the quote before accepting.
Look elsewhere if you want to know what something costs before handing over your medical history — which is most people. HealthRX publishes one price for every dose, MadeMed publishes a price per dose, and CVS Health sells FDA-approved medication at $149 with no litigation risk attached to your supply.
Limitations of This Review
This review is based on independent coverage of MangoRx checked on 7 August 2026. We could not establish Slim pricing at any dose, because it is not published — that is the central finding rather than a gap in our research. We could not identify which states are excluded, the compounding pharmacy, cancellation or refund terms. The Eli Lilly matter is reported as allegations in active litigation; we did not review court filings and no findings of fact should be inferred. The 4.5 shipping and service figures relate to the wider MangoRx business rather than the Slim line specifically. We have not signed up or been prescribed.
Frequently Asked Questions
How much does MangoRx Slim cost?
MangoRx does not publish it. You complete an eligibility questionnaire and medical intake, and a price is quoted after a provider recommends a dose. Get the full schedule including escalated doses in writing, then compare it before accepting.
What is the Eli Lilly lawsuit about?
Lilly alleges the company improperly copied its weight-loss medicines Zepbound and Mounjaro. These are allegations in active litigation, not findings. Lilly has pursued many compounders and telehealth platforms, so it is an industry-wide campaign — but it does create real supply-continuity risk for compounded tirzepatide.
Is MangoRx available in my state?
Around a dozen states are excluded from the Slim line. Check before completing the intake, so you do not disclose your medical history only to find you cannot be served.
Is the medication FDA-approved?
No. The Slim line is compounded semaglutide and tirzepatide, which are not FDA-approved finished products. If you want the approved medication, CVS Health at $149 self-pay or LillyDirect from $299 dispense it directly.
Verdict
2.8 / 5
A newer GLP-1 line from an established men’s health brand, sold with no published price, a dozen states excluded, and active litigation from the patent holder over the tirzepatide.
The wider MangoRx business appears to run well — the shipping and service ratings are good and the company is publicly traded and disclosing. The Slim line is a different question. In a market where identical compounded semaglutide ranges from $69 to nearly $500, refusing to publish any price until a customer has handed over their medical history is the practice we would most like to see disappear from this category, and MangoRx is its clearest example.
Add a dozen excluded states, a thin independent record for this specific product, and Lilly litigation that could interrupt a tirzepatide course mid-titration, and there is little reason to start here rather than somewhere that will simply tell you the price.
Medical Disclaimer & Review Date
This review is general consumer information, not medical advice. GLP-1 medications are prescription drugs with serious contraindications, and whether any treatment is appropriate for you is a decision only a licensed healthcare provider who knows your medical history can make. Nothing here should be used to start, stop, or change a medication.
Details in this review come from MangoRx's own published materials as of the date below. Pricing, medication availability, state coverage, and policies in this category change frequently — verify current terms directly with the provider before purchasing.
Date reviewed: August 7, 2026
Get a Price Before You Give a Medical History
Check your state, then compare against providers that publish their pricing openly before you complete any intake.